Overexpression of miR-99a promoted expansion and suppressed differentiation of hematopoietic stem/progenitor cells

Abstract MicroRNAs (miRNAs) are a class of non-coding RNAs involved in a variety of pathophysiological processes.We have previously reported that the abnormally Oven Element Guard high expression of miR-99a is associated with drug resistance and poor prognosis in acute myeloid leukemia.However, the impact of miR-99a on normal hematopoiesis is not w

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The effects of coloniality and international development assistance on Made in Africa Evaluation: Implications for a decolonised evaluation agenda

Background: It is imperative to recognise the effects of the intrinsically Eurocentric development agenda on attaining transformative evaluation that appropriately addresses development priorities in Africa.The role of international development agencies as critical anchors in African evaluation practice needs examination to advance the Made in Afri

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A Novel Harmonic State-space Modelling Method on the Modular Multilevel Matrix Converter and Coupling Analysis

The fractional frequency transmission system is an FENNEL emerging technology for long-distance wind power integration, and the modular multilevel matrix converter (M3C) is the keen equipment.Since the M3C directly connects two ac grids with different frequencies, the external and internal harmonics have complex coupling relationships with a unique

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Metabolic follow-up at one year and beyond of women with gestational diabetes treated with insulin and/or oral hypoglycaemic agents: study protocol for the identification of a core outcomes set using a Delphi survey

Abstract Background Gestational diabetes (GDM) is associated with an increased lifetime risk for the development of glucose Full Sleigh Bed w/Storage abnormalities, metabolic syndrome, cardiovascular disease, depression and tumours.Despite this high risk of additional comorbidities, there is no standardised approach to the long-term follow-up of wo

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